#Reprogramming

🔬 Join our team in the fight against #cancer! We're looking for a motivated individual to pioneer cellular #reprogramming technology for identifying potent #neoantigens, advancing the frontier of #immunotherapy. Find more information and apply here:

🌟1/7 Check out our new pre-print “A cancer #immunotherapy modality based on dendritic cell #reprogramming in vivo”, where we reprogram #tumor cells in situ to efficiently present antigens as type 1 conventional dendritic cells (cDC1s). How effective is it?

A cancer immunotherapy modality based on dendritic cell reprogramming in vivo #bioRxiv

📢 Exciting news! Our research on #reprogramming #cancer cells into antigen-presenting was featured in @NatImmunol 's research highlights🌟and coined as “Cancer presenting cells”! We are grateful to Nick Bernard for the nice summary! Read more: 🧬

🔬Curious about #reprogramming cancer cells into antigen-presenting warriors? Leveraging the cDC1 transcriptional network with 3 factors, we convert mouse or human cancer cells into immunogenic cDC1s. Explore our step-by-step protocol here #Immunotherapy

#stem_cells #reprogramming Scientists Reverse 60 Years of Aging in Human Cells, Turning 80-Year-Old Cells Into 20-Year-Olds

We are thrilled to announce that our idea to discover immunogenic antigens for cancer #immunotherapy with cellular #reprogramming was granted funding!🎊 A big thanks to the @ERC_Research for the proof of concept grant!😄 #ERCPoC @lunduniversity @Lund_Stem @LuWcmm

Long-term partial #reprogramming can reverse #aging-related epigenetic drift in human skin, especially at PRC2 target regions, restoring youthful DNA methylation patterns, a new study by researchers at @JohnsHopkins, @altos_labs, @KoldLab #Epigenetics

The Illuminati uses various techniques like mind-control programming, black magic rituals, and depopulation schemes but the public is too busy being distracted to notice.

🍃#Reprogramming the Dysfunctional Mind Challenging #SelfSabotaging #Beliefs 🍃🔹 @lisaaromano1 via @youtube

📚5-min read worth of your time:  'Orchestrating an Immune Response to Cancer with Cellular Reprogramming' now published in Genes and Immunity @SpringerNature. We discuss the potential of #reprogramming cancer cells to dendritic cells as a novel cancer #immunotherapy modality!

Article✍️#Reprogramming #gut #microbiota and targeting #CXCL1: The multifaceted mechanism of #PLP1 in #ameliorating alcohol-induced #liver #disease. From Dr. Han @WannanMedicalUniversity; @Sciencedirect; @ElsevierConnect.

A landmark work from the Deng Lab on chemical reprogramming of human iPSCs @Nature. A new chapter of reprogramming! More than 10 years of efforts from multiple generations of friends and lab mates in the Deng Lab!🥳 #hCiPSCs #reprogramming #regeneration

Partial cellular #reprogramming modulates downstream epigenetic states and rejuvenates cellular phenotypes, yet it cannot identify the upstream root trigger that drives aging. If this root cause persists, new degenerative changes will still occur. This stems from inherent limitations in the research methodology of conventional Western medicine, rather than the failings of individual clinicians or researchers. See my attached article.

Excited to share our paper in @CellRepJrnl co-authored by our CSO @eskamoah which shows extension of median remaining lifespan in extremely old wild-type mice accompanied by improved health outcomes via systemic AAV-based partial reprogramming therapy: 🧬

Happy to share the link to my SCOG online lecture on #oncofetal #reprogramming and #Immunotherapy in the #RAS driven #childhood #leukemia JMML, using #multiomics analyses on #stemcells. @singlecellomics @DKFZ @NCT_HD @TMO_Heidelberg @TransCanEpi

Come to Manchester!! Such an exciting time with the launch of the @wellcometrust Discovery Research Platform for Cell-Matrix Biology- #matrix #reprogramming See more 👇 & contact us for more information-

I am thrilled to finally share our work on the limiting role of vitamin B12 in #OSKM #reprogramming and tissue repair, out today it in @NatMetabolism Read it here!! 🥳🧪👩‍🔬🔬 1/n

Exited to share our latest findings on the transcription factor KLF7 as a promoter of human pluripotency. #pluripotency #reprogramming #stemcells For more details, have a look at our pre-print below👇 🧵1/11

📢 Bridging direct cell reprogramming and cancer immunotherapy: our new study on reprogramming cancer cells into antigen-presenting dendritic cells (Tumor-APCs) is out @SciImmunology. Read on to know more. #ScienceResearch #reprogramming

I am excited to become the new Editor-in-Chief of Cellular Reprogramming and foster the growth of this dynamic field! I am honoured to build on the the legacy of Sir Ian Wilmut, famous for cloning Dolly the sheep. Stay tuned! #Reprogramming @LiebertPub @lunduniversity

NEW: In vivo partial #reprogramming by OSKM expression is effective in delaying natural #aging-related molecular and physiological phenotypes @KristenBrowder @genentech @salkinstitute