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A clinical practice statement from the Obesity Medicine Association highlights two distinct but interconnected pathways through which obesity contributes to cardiovascular disease (CVD) — one driven by the mechanical burden of excess body fat and the other by dysfunctional adipose tissue. Understanding these pathways may help clinicians better assess cardiovascular risk and recognize the importance of treating obesity itself rather than only its downstream complications. Tap the link to read more:4471.3K
Nearly 3 in 4 former National Football League players who died between 2008 and 2023 likely had chronic traumatic encephalopathy, a new study suggested. The population-based cross-sectional analysis included more than 2300 former NFL athletes who played an average of 5 years and died during the 16-year study period, nearly 400 of whom were brain donors. Among donated brains with a determined CTE status, 93.5% showed evidence of the CTE neuropathology. That isn’t necessarily surprising, researchers said, since players with symptoms of CTE during life were about five times more likely to be brain donors. The study was published online on October 28 in JAMA Network Open. Read more at the link:0031.1K
Chronic diarrhea is a common clinical presentation that may arise from a wide range of gastrointestinal and systemic processes. Clinical evaluation should first characterize the diarrhea and its context, then apply focused examination to identify treatable disease and exclude important organic pathology. Test your knowledge of chronic diarrhea with this quick quiz:1331.5K
Sjögren disease can cause painful dry eyes and dry mouth, and there’s no approved drug targeting the underlying disease. A new observational study found that patients who also had type 2 diabetes and took metformin had less gland inflammation. Researchers say it’s a promising signal, but randomized trials are needed.25202.4K
Think automated insulin delivery is too complex for primary care? Dr. John E. Anderson, Davida F. Kruger, and Casey Wells break down why AID systems are actually easier to manage than traditional injections. Watch the full discussion ➡️ #CME #Diabetes #PrimaryCare1121.3K
Key Voices in OSA: Exploring the Lived Experience of OSA: Bringing Light to a Dark Situation0211.1K
"I've watched enough tubes fill with my own blood to understand the excitement that helped land Elizabeth Holmes on the cover of Fortune in 2014. I'm guessing I'm not the only one: The movie theater was packed when I went to see You Can See Everything on its opening weekend. Elizabeth Holmes had some explaining to do, and apparently plenty of us wanted to hear it. Her blood-testing company, Theranos had promised extensive testing results from a few drops taken from a fingertip. At one point during the film, she brings out pieces of a Theranos machine and arranges them on a table. According to Holmes, the machine could run any medical test, though she and Fielder soon got stuck on the word “can.” Could it run those tests now? Well, no, not exactly, Holmes clarified. She meant that it could once someone developed the necessary chemistry. Even while Holmes was explaining away the missing chemistry, it sounded like something worth figuring out. Researchers are already getting useful results from small blood samples, and some can measure thousands of molecules. But is any of it bringing us closer to what Holmes promised?" Read more about why a few drops of blood still can't deliver what Theranos promised, and the researchers working to change that:0231.4K
Starting in 1 HOUR ➡️ Bridge patient advocacy with clinical insights. Join our expert panel LIVE for our Key Voices in OSA social media event! 🗓️ Today ⏰ 3:00pm ET #SleepApnea #MedEd #Healthcare1021.4K
A three-part JCI study offers the first clear evidence in older adults that sarcopenia-related weakness stems from impaired nerve-muscle communication, not just lost muscle mass, which helps explain why weights and protein often fall short. The researchers also found a drug target that restored muscle function in aged rodents. Thomas W. Buford, PhD, of UAB, who wasn’t involved, called it impressive for combining human data, multiple rodent species, and a reversible, specific mechanism.7241.4K

















