CD Genomics

Bulk m6A is an average over millions of cells. m6A-ARTR-DBiT reads the mark in situ on tissue sections and barcodes cDNA spatially — ~20 µm pixels, regional m6A maps in mouse brain. #m6A #SpatialOmics

FIONA1 deposits m6A at the 3' end of FLC. That mark stabilises the mRNA; unmethylated FLC is degraded fast, and flowering time shifts. mRNA-seq + Nanopore direct RNA-seq (CD Genomics) + MeRIP-seq. #m6A

Most m5C in a total RNA prep sits on tRNA and rRNA. If your claim is about mRNA, depletion has to show in the mapping stats. Bisulfite, oxBS or RIP — the assay decides what you can see. #m5C #Epitranscriptomics

m6A-seq locates m6A within ~100 nt, not at a base. Fragment size sets the resolution ceiling — a peak is a window, not a coordinate. Peak calling, DRACH QC, differential methylation. #m6A

Cancer's circular ecDNA survives via Polθ-mediated MMEJ repair at TA-repeat breakpoints. Block MMEJ (not NHEJ/HR) → selective ecDNA loss → weakened tumors. Billing et al., Nature 2026. #ecDNA #CancerResearch #nature

Customer case: the CLK2/SRSF9 splicing axis drives AR-V7 in prostate cancer. Van Goubergen et al. (Mol Oncol 2025) used nanopore sequencing provided by CD Genomics for isoform-resolved transcripts. #LongReadSequencing #CancerGenomics

2 mL plasma, 1–5x WGS. cfDNA fragmentomics reads fragment sizes, end motifs, nucleosome footprints, CNV — a tissue-origin signal beyond mutations. Full service + pipeline: #LiquidBiopsy #cfDNA #NGS

~17% of tumors carry oncogenes on extrachromosomal circles — standard WGS barely sees them. Circle-enriched sequencing + eccDNA bioinformatics. #eccDNA #NGS #CancerResearch

11,692 genes silenced. 2.5M single cells profiled. A genome-scale CRISPRi atlas of human iPSCs (Nat Biotechnol, 2026) maps how genotype shapes cell state — data and pipelines fully open. #CRISPRi #iPSC

A genome-wide CRISPR screen in haploid hESCs revealed ATF7IP as a suppressor of paternal imprinting (Nat Commun). RRBS library prep & sequencing for the methylation maps: provided by CD Genomics. #CRISPR #Epigenetics

The RNA you want may not be in cells — it's in transit. Exosomal RNA sequencing: miRNA, mRNA & lncRNA from serum, plasma, urine, or culture supernatant. #Exosomes #LiquidBiopsy

Pooled CRISPR screens live or die on the readout. CRISPR screen sequencing + MAGeCK analysis: sgRNA abundance, fold changes, ranked gene hits from 5×10⁶ cells or ≥1.5 μg gDNA. #CRISPR

Pathogenic germline variants raise childhood cancer risk ~12-fold. Among 75,602 children sequenced before age 3, carriers developed malignancies at 3.23/1,000 person-years. Genes: NF1, TSC2, RB1, WT1. #CancerGenetics

How RNA-seq untangled self-compatibility & oil biosynthesis in noug, an underutilized oilseed crop. Authors used RNA sequencing & analysis provided by CD Genomics. 🌱 #RNASeq #PlantGenomics #CDGenomics

qPCR answers one question. NGS answers the ones you didn't know to ask. HBV/HPV/EBV capture, tNGS, and 16S profiling for bacteria, viruses, fungi, and parasites. #PathogenSequencing

CD Genomics hereditary cancer panel: 37 genes, amplicon NGS, >1000× depth, SNV/InDel/SV detection. From 200 ng gDNA — blood, saliva, tissue, or FFPE. #HereditaryCancer #NGS

Rare variant GWAS associations can be confounded by structure, assortative mating, and family effects. UK Biobank study:

Plant-protein fishmeal replacement alters rainbow trout gut microbiota and astaxanthin pigmentation. 16S/18S/ITS sequencing by CD Genomics:

tRNA sequencing decodes full tRNA sequences, modifications, and charging status directly. CD Genomics:

Ribo-seq captures what ribosomes are translating at codon resolution. CD Genomics end-to-end service: