ashe @ashebyteson the physics of intelligence & being human in conversation with @beffjezos 04:30 the masks we learn to wear 21:43 thermodynamic computing 32:52 the origins of e/acc 56:06 forgiveness & boundaries 1:01:41 keeping an open heart
Superpower @superpowerWe're thrilled to announce the Superpower Peptide Library. Every peptide, mapped to the body. 152 peptides, from approved drugs to compounds still in trials, sorted by where they act. Each one has its own page, reviewed by a physician and fully cited, covering: - the evidence and how strong it is - its FDA status - it's mechanism of action - what studies in humans have found Because not all peptides are equal. Semaglutide is FDA-approved. BPC-157, maybe the most talked-about peptide for recovery and repair, is not. In a 2025 review of its research, 35 of 36 studies were in animals or the lab. Know the science before you buy the hype. Check it out here:
PaulS @paul_s_1738
Lisa LaBelle @SpaceWarriorX
Shay Boloor @StockSavvyShayAnthropic says Claude Mythos could bring quantum computing “within reach sooner” after designing circuits that make a critical operation ~17x cheaper. What makes this interesting is AI can now design, test and improve these circuits on its own so that opens the door to faster breakthroughs across quantum computing without waiting for better hardware.
Ethan Lambeth @LambethEthanCoin labs is announcing our new decision model Flip-1. - Distilled down to 1 parameter - 50% on yes/no bench - Runs fully offline
Mark Zuckerberg @finkdIntroducing Muse Wonder, our new family of frontier models with state of the art performance for personal and professional agentic work.
Beff (e/acc) @beffjezosHere's the e/acc manifesto transcripted in Accelerando glyph alphabet
Rob Leclerc @robleclerchas a group so esteemed ever crashed out this bad? i always saw mathematicians as the high priests of truth and intellectual integrity, but ai comes along solves a few problems and the exposed themselves as just another group of status hungry individuals. how they can’t see this as the beginning—not the end—is beyond me.
Anjney Midha @AnjneyMidhahundreds of MI355x and B300 nodes now live on subsidized for all .edu and .govs it’s time to scale the frontier ecosystem for the public benefit
Beff (e/acc) @beffjezosAI is a telescope for concept space The bigger the model, the further out we can peer into the void of complexity
will depue @willdepuei asked GPT 6 Pro and Fable 5.1 to rank all discoveries in the last three years 🔵 for Human discovered 🔴 for AI discovered (before October 6th) 🟢 for AI discovered from OpenAI/math repo 81% of them have been released today. wtf
Beff (e/acc) @beffjezosDisaggregated inference is the future. Great panel with @general_compute discussing their heterogenous compute cloud, the speciation of compute for disaggregated inference, and how thermo compute will fit in the picture More coming soon. Stay tuned 😉
Dr Chiara Mingarelli @Dr_CMingarelliTomorrow is the day for the Nobel prize in physics! What are your predictions?
