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Ashley Laughney
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Ashley Laughney

@LaughneyLab

Associate Professor @weillcornell @wcm_MeyerCancer Systems Biology of Metastasis

934 Following1.6K Followers507 Posts
  1. Ashley Laughney@LaughneyLab
    !! Recruiting postdocs in deep learning and graphs, dynamical systems, & computational biology to map the context-dependent effects of multicellular programs and pleiotropic proteins in cancer progression. We can provide exciting, first-in-class data!
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  2. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @UTMDAnderson: Early findings from a first-in-human trial of VLS-1488, an oral KIF18A inhibitor, show promising anti-tumor activity in heavily treated ovarian cancer. No dose-limiting toxicities were observed. Presented by Dr. Ecaterina Dumbrava at #ASCO25. #EndCancer
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  3. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @Samuel_Bakhoum: (1/2) A very exciting milestone for ⁦@VolastraTx⁩ and the field of #Chromosomal_Instability. Early escalation data for our KIF18A inhibitor, VLS-1488, show excellent safety and promising efficacy in heavily pre-treated ovarian cancer patients.
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  6. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @WCMEnglanderIPM: We hope to see you Thursday for the next @WCMEnglanderIPM #PrecisionMedicine Journal Club presented by @cbm_student @EthanEarlie on Thursday, April 24th from 3-4 pm in Belfer #1401 and via Zoom (DM for details)!
    WCM Englander Institute for Precision Medicine @WCMEnglanderIPM
    The next @WCMEnglanderIPM #PrecisionMedicine Journal Club will review the @Nature article "MHC Hammer Reveals Genetic and Non-genetic HLA Disruption in Cancer Evolution," presented by @cbm_student @EthanEarlie April 24th from 3-4 pm in Belfer #1401 and via Zoom (DM for details)!
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  8. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @JCubRuiz: Our new study published today @Nature uncovers that Transgelin 2 preserves T cell lipid metabolism and anti-tumor activity. Transgelin 2 is silenced in dysfunctional TILs, and restoring its expression enhances CAR-T cell therapy in #OvarianCancer 👇
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  9. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @GeiselMed: Congratulations to Dr. Victor R. Ambros, former member of the @dartmouth Dept. of Biological Sciences and Geisel Dept. of Genetics, for being awarded the 2024 #NobelPrize in Physiology or Medicine, for the discovery of microRNA.
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  11. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @NickyMcGranahan: Together with @CharlesSwanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use… 🧵below
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  13. Ashley Laughney@LaughneyLab
    Micronuclear collapse triggers chronic STING signaling that drives metastasis. But how do they rupture?? Beautiful work from the @Samuel_Bakhoum lab, led by brilliant physicist turned hard core cell biologist @melodyDiBona, explains how..
    Science Magazine @ScienceMagazine
    Micronuclei are frequently observed in tumor cells as a result of aberrant chromosomal separation. Two new Science studies investigate the cellular processes involved in micronuclear collapse. Learn more in this week's issue:
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  14. Science Magazine✓@ScienceMagazine
    Micronuclei are frequently observed in tumor cells as a result of aberrant chromosomal separation. Two new Science studies investigate the cellular processes involved in micronuclear collapse. Learn more in this week's issue:
    Download
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  16. Ashley Laughney@LaughneyLab
    Ashley Laughney
    RT @dschweppe1: Very happy to have DNA O-MAP out! The DNA version of this work, started from a simple premise: how can we measure the proteome at any genomic loci in (nearly) any cell? This was a great collaboration with @oligopain, and led by Yuzhen Liu and @CD_McGann. 1/8🧵
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  21. Ashley Laughney@LaughneyLab
    Sincerest of thanks to the @psscra for supporting scientists, taking risks on new ideas, and to the amazing teams working to realize them! Congrats to all awardees.
    Pershing Square Sohn Cancer Research Alliance @psscra
    We are so excited to announce our five winners of the 2024 Pershing Square Sohn Prize. These five brilliant scientists are: 1. Santosha Vardhana, MD, PhD 2. Juan Pablo Maianti, PhD 3. Ashley Laughney, PhD 4. Teresa Davoli, PhD, 5. Samuel Bakhoum, MD, PhD
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  22. Pershing Square Sohn Cancer Research Alliance@psscra
    We are so excited to announce our five winners of the 2024 Pershing Square Sohn Prize. These five brilliant scientists are: 1. Santosha Vardhana, MD, PhD 2. Juan Pablo Maianti, PhD 3. Ashley Laughney, PhD 4. Teresa Davoli, PhD, 5. Samuel Bakhoum, MD, PhD
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