Dr. Tim Lüddecke

@LuddeckeTim

Biochemist/Zoologist studying🕷️🐍🐜🐸 toxins. PI of Animal Venomics Lab @Fraunhofer_IME & @LOEWE_TBG | #firstgen #newPI #LINO23Alumnus

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  1. Dr. Tim Lüddecke@LuddeckeTim
    Happy to share that this small friend was born today! My Habilitation, officially submitted, contains 20 papers on venom biodiscovery and Evolution on ca. 400 pages. Thanks to my amazing team and colleagues who made this possible! @Tschosei @HurkaSabine et al
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  2. Dr. Tim Lüddecke@LuddeckeTim
    Newest paper from the lab out at Biotechnology Advances! Spearheaded by my brilliant postdoc @DammMaik, we take a deep-dive to #Ms-#Imaging in #zootoxinology. The manuscript contains a quick guide to the technology, a summary of how it has been used so far, and a reflection on hurdles to overcome alongside future developments. So, if you are up to study venoms or poisons with MSI, our new paper might be a good read! @Fraunhofer_IME @Fraunhofer @ProLOEWE @Senckenberg @jlugiessen
    Maik Damm 🐍 @DammMaik
    📄 New Publication by our Animal Venomics Lab! We mapped the architecture of #toxin systems by #MSImaging. First overview of MSI in #zootoxinology and future applications. 🔓#OpenAccess Damm et al. 2025 - #MassSpec #venom @LuddeckeTim @Fraunhofer
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  3. Dr. Tim Lüddecke@LuddeckeTim
    Thrilled to share that the #Fraunhofer society recently released an issue of the Fraunhofer magazine which highlights all the antiinfectives research done across the different institutes. A snippet of that article features my lab’s effort to transform 🕷️🐍🦂 toxins into life-saving antibiotics. If you’re interested in what toxic critters can do for your health, proceed to the open access article here: @ProLOEWE @LOEWE_TBG @Fraunhofer_IME @Fraunhofer @geobiodiversity @jlugiessen
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  4. Dr. Tim Lüddecke@LuddeckeTim
    Dr. Tim Lüddecke
    RT @Spektrum_BIO: Wissenschaftler:innen des LOEWE-Zentrums für Translationale Biodiversitätsgenomik (TBG) entdeckten in Spinnengiften eine große Vielfalt von Enzymen, die für eine bioökonomische Anwendung interessant sein können. Foto: Louis Roth
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  5. Dr. Tim Lüddecke@LuddeckeTim
    Dr. Tim Lüddecke
    RT @DGHTeV: Unsere Internationale Fachtagung zur Kreuzotter findet wie bekannt vom 22. - 24.11.2024 in Augsburg statt. Zur Anmeldung: Die aktuellsten Informationen zur Tagung finden Sie immer auf unserer Tagungshomepage unter
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  6. Dr. Tim Lüddecke@LuddeckeTim
    Newest lab paper out in @npjbiodiversity spearheaded by my stellar PhD student @Tschosei looking into the neglected realm of 🕷️ #venom #enzymes. When you look into 🕷️📖, you will read that their venoms are mostly composed by neurotoxins and that enzymatic compounds are rare. Recent works challenged this perspective and thus we set out to investigate this question closer. We reanalyzed the venomic data from the last 20 years (!!!) and searched for enzymes. Indeed, we found that spider venoms can harbor dozens of them and that >140 enzyme families are present in venom across the 🕷️kingdom. This not only means that we have so far vastly underestimated the chemical diversity of 🕷️venom, but it also opens up new avenues for #biodiscovery. How? Well, enzymes are important for diverse industries and sometimes reach billion-dollar level market sizes. We believe that this hitherto unrecognized toxinological dark matter has tremendous translational #value and recovering it will be a future major research line of my lab. @ProLOEWE @LOEWE_TBG @geobiodiversity @Senckenberg @Fraunhofer_IME @Fraunhofer @jlugiessen
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  7. Dr. Tim Lüddecke@LuddeckeTim
    Newest paper from the lab, the first dissertation chapter of my amazing PhD student Lennart Schulte and the first outcome of my @dfg_public grant „FunVen“ published in @royalsociety Open Science. Fully black (i.e. melanistic) adders are in Central European folklore referred to as hell adders since it’s believed that their dark color is linked to evil forces and the devil. Of course these snakes are also believed to be more toxic. Here, we investigate this case and compare venom chemistry and activity between hell adders and normally colored congeners. Indeed we find minuscule differences which are likely attributable to normal intraspecific variations and are unlikely to be of clinical consequence, hence the tale of more toxic black adders seems to be exactly that - a tale. @ProLOEWE @LOEWE_TBG @geobiodiversity @Fraunhofer_IME @jlugiessen @VIPERA_eV @AntiviralGroup
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  8. Dr. Tim Lüddecke@LuddeckeTim
    Dr. Tim Lüddecke
    RT @MarkScherz: I am thrilled to announce I have secured an @ERC_Research Starting Grant (1.5 MILLION euros!) to study the #genomics of miniaturisation in vertebrates! Press release:
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  9. Dr. Tim Lüddecke@LuddeckeTim
    Hey fellow venom ECRs, At the last IST conference in Singapore, a major topic was the need to establish a better networking platform form the next generation of toxinologist. As such (with some delay) I have set up a dedicated X community for us, where we can exchange on all topics relevant. The content needs, of course, to be posted from its members, so a first step would be to catch as many venom/toxinology ECRs as possible. So please, follow the link below and join in if you are interested. This could be a first step towards a better network among the young venom researchers!
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