Stainier Lab

Christopher Dooley @CMDooley77

Huge thanks to @ACHSEeV, the Köhler Foundation, and our brilliant team @StainierLab @MPI_HLR. Science is a team effort, and this award recognizes that shared dedication. More here 👉 #RareDisease #EvaLuiseKöhler #Duchenne #DMD #TranscriptionalAdaptation

StemCellReports @stemcellreports

The newest podcast is now live. Listen here or wherever you download your favorite podcast. @ISSCR @paolo_panza @StainierLab @MingxiaGu @UCLAstemcell

Christopher Dooley @CMDooley77

🧵Excited to share our new paper on transcriptional adaptation and the role of RNA destabilization in triggering a TA-like response. Read the full study here 👉 [1/6]

Thomas Juan @TJ_ThomasJuan

Very proud to share my latest research on a novel biotechnological tool: The first use of a self-cleaving ribozyme to knock down an endogenous gene in a vertebrate model. Thanks to the @StainierLab and to my co-authors #PLOSGenetics:

Christopher Dooley @CMDooley77

5/5 🌟 Why It Matters: First evidence of TA in humans! This work rethinks DMD treatment, showing mRNA decay itself can drive genetic compensation. Kudos to 1st Lara! @DouglasAdamoski @TJ_ThomasJuan & team! @MPI_HLR 🎉 #RareDisease

Brian Juvik @BrianJuvik

Excited to share this article, where we highlight the possibility that dysregulation of genes via transcriptional adaptation, an mRNA feedback loop, may play a role in some dominant diseases. @StainierLab A new hypothesis to explain disease dominance

Yanli Xu @Yanli_Xu_

Thrilled to share my PhD work published in @NatureCVR ! This journey was challenging, but persistence and dedication truly paid off. A huge thank you to all my co-authors for their support, and especially to my supervisor, Didier Stainier (@StainierLab ), for his guidance!

Development @Dev_journal

flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response Read this #OpenAccess Research Article by Zhen-Yu Wang, @rmarinjuez and colleagues:

Maëlle Bellec @BellecMae

And our embryo is on the cover 😍

Radha Kulkarni @radha_kul

Grateful to all ICDAR 2024 organizers for giving me this great opportunity to present my work! 🎉 Also a big shoutout to @StainierLab members for their constant support!