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👥5,530, excess weight + ⤴️CV risk (CVD, CKD or ⤴️ risk)
⚖️Survodutide vs placebo
📊5-point MACE HR 0.89 (95% CI 0.67–1.18)
⚠️Noninferior; superiority unproven
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NEJM @NEJMAmong patients with atherosclerotic cardiovascular disease, targeting an LDL cholesterol level below 55 mg per deciliter led to a lower 3-year risk of cardiovascular events than targeting a level below 70 mg per deciliter. Full Ez-PAVE trial results and Research Summary:
Roger Blumenthal @rblument110 prevention takeaways from ‘25 high blood pressure guideline - Excellent summary by @CiccaroneCenter @hopkinsheart ⭐️ 🫀 Fellow @AaronTroyMD & Guideline Writing Group Member & 🏍️ enthusiast Stacey Schott @ChiadiNdumele