#CellCycle

New Perspective: Gilles Hickson revives a material-processing view of #cytokinesis, asking how a shrinking membrane–cortex interface sustains closure despite continued material inflow. #CellCycle #CellDivision #Cytoskeleton

Faithful #mitosis depends on precise regulation of #separase. Learn how Sak1/LKB1 activates separase and promotes its nuclear localization. @copondeciencia et al. reveal a novel regulatory mechanism conserved from yeast to humans. #CellCycle #CellBiology

🚨Thrilled to share our lab’s first paper!🚨Excited to present our discovery that the #cytoplasm can divide without #nuclei, and do this periodically independently from the #cellcycle oscillator! "Oh?! What’s the mechanism and function” I hear? 1/🧵👇🏼

Plasek-Hedge et al. show that Malat1, a #lncRNA thought to be exclusively nuclear, highly abundant, & very stable, in fact localizes to the cytoplasm in early G1, where it is degraded at the onset of each #cellcycle by a translation-mediated decay pathway

Check out our latest work on cell cycle inhibitors, which has implications for how cancer cells could become resistant to these drugs #senescence #cellcycle #Cancer

Selective regulation of kinesin-5 function by β-tubulin carboxy-terminal tails. New study from Ezekiel Thomas and Jeffrey Moore @CUAnschutz: #Cytoskeleton #Biochemistry #CellCycle #CellDivision

More #gastruloids papers now starting to be used to test #CellBiology - #CellCycle and #Cilia –

Glutathione accelerates the #cellcycle & cellular reprogramming in #plant regeneration @Dev_Cell Very pleased of this joint effort with @KenBirnbaum, Laura Lee et al, combining scRNAseq & cell cycle #PlaCCI @CBM_CSIC_UAM @b_desvoyes

Ani Michaud, @GoryachevAndrew, George von Dassow, William Bement @BementLab, et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, and RGA-3/4. #CellCycle #CellDivision #Cytokinesis #cytoskeleton

第二著者ではありますが、論文がNCBにPublishされました！ Happy to share our latest work from @francisabarr lab is now published in @NatureCellBio #cellcycle @BiochemOxford 👉MDM2 functions as a timer reporting the length of mitosis | Nature Cell Biology

In @SciSignal, a team demonstrates that the modification of the chromosomal passenger complex—a protein complex that’s critical for the #CellCycle—determines the pluripotency of embryonic stemlike cells.

In @SciSignal, a team demonstrates that the modification of the chromosomal passenger complex—a protein complex that’s critical for the #CellCycle—determines the pluripotency of embryonic stemlike cells.

Ever wondered how CDK4/6 inhibitors slow cancer? • Block CDK4/6 • Rb stays shut • E2F can’t enter nucleus • Cell stuck in G1 Small blockade → big impact #BreastCancer #CDK46 #CellCycle #Oncology #TargetedTherapy #MVOnco

In @JCellBiol, Ani Michaud, @GoryachevAndrew, George von Dassow, William Bement et al. identify Ect2 and RGA-3/4 as core components of the cortical excitability circuit associated with #cytokinesis. #CellCycle #CellDivision #cytoskeleton

Membrane compartmentalization of Ect2/Cyk4/Mklp1 and NuMA/dynein regulates cleavage furrow formation, say Shrividya Sana @SanaShrividya, Ashwathi Rajeevan & Sachin Kotak @Sachin_mitosis @iiscbangalore: #CellCycle #CellDivision #Cytoskeleton #cytokinesis

Diurnal control of H3K27me1 deposition shapes expression of a subset of #cellcycle & #DNAdamage response genes #Arabidopsis #atrx5 #atrx6 #BRCA1 #RAD51 #PARP1 #gene_silencing @ThePlantJournal

King, Wettstein, Ünal, et al. @berkeleyMCB reveal that nuclear pore complexes undergo two distinct remodeling events during budding yeast #meiosis: partial and full nuclear basket detachment. #Genetics #CellCycle #CellDivision #Organelles

A proteome-wide yeast degron collection for the dynamic study of protein function. New tool developed by Rosario Valenti, Yotam David, Maya Schuldiner and colleagues @WeizmannScience: #CellCycle #CellDivision #Technology #CellMetabolism

It's not too late! Join #ScienceWebinars on July 8 at 12p ET for our next free, educational webcast: Deciphering the cell cycle: The role of the cell cycle in cancer Sign up today! #webinar #CellCycle #CancerResearch

Live-cell imaging of chromosome oscillation in RPE-1 or HeLa cells treated with taxol, BTB-1, and UMK57 or depleted of Kif18A. From a study by Iemura @ieken5916, Tanaka and colleagues @IDAC_TohokuUniv. #Cancer #CellCycle #CellDivision