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Posts with #JAXstemcellsdev

#JAXstemcellsdev

Public posts on X that use #JAXstemcellsdev.

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  1. Jennifer Trowbridge@TrowbridgeLab
    Very grateful for the support of @TheMarkFdn to pursue our biggest and boldest ideas!! #BloodCancerAwarenessMonth #JAXresearch #JAXstemcellsdev
    The Mark Foundation for Cancer Research @TheMarkFdn
    This #BloodCancerAwarenessMonth, we’re spotlighting 2023 Emerging Leader Award winner Jennifer Trowbridge (@TrowbridgeLab) of @JacksonLab. She’s looking for answers to a big question: why aging blood cells develop into cancer in some individuals but not others.
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  4. Jennifer Trowbridge@TrowbridgeLab
    Peter @vangalenlab and I are very appreciative and grateful for the support of the Waxman Institute @WaxmanCancer to pursue our exciting collaborative studies! #BloodCancerAwarenessMonth #JAXresearch #JAXstemcellsdev
    Waxman Institute @WaxmanCancer
    We're proud to fund @TrowbridgeLab & @vangalenlab as they investigate how age-related inflammation may fuel blood cancers—and uncover potential paths to prevention. This is why connecting aging biology & cancer research matters! with @TheMarkFdn #BloodCancerAwarenessMonth
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  6. Jennifer Trowbridge@TrowbridgeLab
    The ear has a backup! 😮Auditory hair cells can self-correct their orientation after birth even without proteins thought to control it. Congrats to the Tarchini lab, part of our Stem Cells & Development program at JAX! 🎉 #JAXresearch #JAXstemcellsdev
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  7. Jennifer Trowbridge@TrowbridgeLab
    Thrilled to share that our Stem Cells & Developmental Biology program at JAX is officially launched. 40 PIs. 60+ trainees. >$160M in active NIH funding. Fundamental discovery and translational platforms — in the same world. 🔬 #JAXresearch #JAXstemcellsdev
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  8. Jennifer Trowbridge@TrowbridgeLab
    Excited to welcome Dr. Laura Bennett to JAX and our Stem Cells & Developmental Biology group this fall! Trained with Nancy Speck at UPenn, Laura's rigorous & translationally-minded program on HSC development is a perfect fit. Details below! #JAXresearch #JAXstemcellsdev
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  9. Jennifer Trowbridge@TrowbridgeLab
    @ISSCR
    @ISSCR 2026 is almost here (July 8–11, Montréal)! Our JAX Stem Cells & Developmental Biology colleagues have 3 talks and 9 posters across the meeting, plus a JAX-NYSCF Innovation Showcase and Booth #605. Here's the full picture 👇 #ISSCR2026 #JAXresearch #JAXstemcellsdev
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  10. Jennifer Trowbridge@TrowbridgeLab
    Congrats to our Stem Cells & Development colleague Stefan Semrau! Support from the Michael J. Fox Foundation will launch human stem cell models of Parkinson's disease to be shared with the research community. More below! #JAXresearch #JAXstemcellsdev
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  11. Jennifer Trowbridge@TrowbridgeLab
    1/3 Delighted to have visited @UPenn this week, hosted by the fantastic Dr. Bobby Bowman who has built an exciting research program on the origins of myeloid malignancies and leukemia relapse.
    Download
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  12. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    2/3 Wonderful to reconnect with so many outstanding colleagues and friends like @GillSaar, Nancy Speck, Celeste Simon, Vikram Paralkar, Peter Klein, @kathrinbernt, Martin Carroll, Sarah Tishkoff, and a truly impressive cohort of trainees.
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  13. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    3/3 A highlight was sitting down with Dr. Laura Bennett to discuss her upcoming lab launch at JAX. Her arrival is a major addition to our Stem Cells & Developmental Biology program, and a sign of exciting things ahead! #JAXresearch #JAXstemcellsdev
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  15. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    This may reach beyond the bone marrow. Clonal expansion happens broadly in tissues including skin, colon, and esophagus. If senescence-driven niche remodeling turns out to be a general feature of pre-malignant clones, it could matter across multiple tissue contexts.
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  17. Jennifer Trowbridge@TrowbridgeLab
    New preprint from our lab led by @jaynathemistry! 🧬 We asked: what upstream signal ignites the inflammatory cycle that drives clonal hematopoiesis (CH)? Answer: neutrophil-derived S100A8/A9 alarmins. 🧵1/4
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  18. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    Tasquinimod (S100A9 inhibitor, now in Phase I/II for myelofibrosis) selectively reduces: ✔️ TNFα & IL-6 production from mutant cells ✔️ Dnmt3a-mutant HSPC frequency ❌ Normal hematopoiesis unaffected Inspired by the foundational work of Helene Gleitz & Rebekka Schneider. 3/4
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  19. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    Key implication: this alarmin-driven inflammatory axis is active before overt malignancy. Thus, targeting it at the CH stage could suppress mutant stem cell expansion early. #JAXresearch #JAXstemcellsdev 4/4
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  20. Jennifer Trowbridge@TrowbridgeLab
    Day 2 of #ISSCR2026 🔬 🎤 Stefan Semrau: AI-driven phenotyping of 309 iPSC lines uncovers Parkinson's morphological signatures | 3:00 pm, Room 510a 🪧 Morgan Brady T1323: genetic variation + mESC differentiation
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  21. Jennifer Trowbridge@TrowbridgeLab
    @TrowbridgeLab
    🪧 Cullen Clairmont T1275: modeling intracranial germ cell tumors w/ hPSCs 🪧 Christopher Baker T1404: genome regulatory incompatibilities in diverse mESCs Exhibit Hall, Rm 220 | Booth #605 #JAXresearch #JAXstemcellsdev #NYSCF
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  22. Jennifer Trowbridge@TrowbridgeLab
    The Jackson Laboratory is a wonderful, collaborative place to pursue basic & translational science. On the faculty job market? I strongly encourage you to consider joining us in Bar Harbor, Maine! Apply: #JAXresearch #JAXstemcellsdev
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  23. Jennifer Trowbridge@TrowbridgeLab
    Day 1 of #ISSCR2026! Big day for JAX & NYSCF: 🍽️ 12:30 pm — JAX-NYSCF Innovation Showcase: scalable iPSC platforms for neurodegeneration | Room 510a (lunch provided) 🎤 3:10 pm — Daniel Paull: scaling iPSC models for drug discovery | Room 510a #JAXresearch #JAXstemcellsdev
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  25. Jennifer Trowbridge@TrowbridgeLab
    Day 3 of #ISSCR2026 🔬 JAX stem cells & development colleagues present new translational work on diabetes and vision loss! 👇 Final day tomorrow, and something special for JAX. Stay tuned. 🏆 #JAXresearch #JAXstemcellsdev
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