#TwitterHomework

Medullary thyroid carcinoma🔬 A neuroendocrine tumor that arises from parafollicular cells(C cells), which secrete calcitonin*; composed of solid nests of discohesive cells within a fibrous stroma that might contain amyloid* ~RET oncogene ~MEN2 syndromes #twitterhomework @KMirza

One of the cases today was angioimmunoblastic T-cell lymphoma. It is a peripheral T-cell lymphoma of T-follicular helper cell origin. #twitterhomework @KMirza

Today is the day of reading Robbins 🤓 3 principal nonproliferative breast changes: 1) cystic change, often with apocrine metaplasia 2) fibrosis 3) adenosis (an increase in the number of acini per lobule) #Twitterhomework @KMirza

Saw a Merkel cell carcinoma today - an uncommon neuroendocrine tumor, and learned that it associated with Polyomavirus infection. #twitterhomework #PathElective @KMirza

PFA-100 The result is dependent on: - PLT function - Plasma vWF level - PLT number - Hct FP: - Low PLT count or Hct - Specimens >4 hrs old - Sent through pneumatic tubes FN: - Mild vWD - Many PLT function defects - Connective tissue disorders #twitterhomework @KMirza

Pleomorphic adenoma🔬 Triphasic salivary gland tumor (mostly in parotid) with ductal cells, myoepithelial cells, and stromal component Pseudopods are common ✨Tyrosine crystals(dense amorphous eosinophilic floret-shaped) can be seen but not specific! #twitterhomework @Kmirza

The parathyroid glands are tiny endocrine glands that play a crucial role in calcium homeostasis by secreting the peptide hormone, PTH. On histology, these glands are composed mainly of fat cells, chief cells (secrete PTH), and oxyphil cells. #Twitterhomework #Histology @KMirza

Caroli disease: - genetic condition (AR) - ↑ risk of cholangiocarcinoma - the cysts are communicating with the functional biliary system (vs polycystic liver disease) - 🔬dilated ducts lined by cuboidal or columnar epithelium with fibrotic duct wall #twitterhomework @KMirza

Okay #digitaldesign class...what kind of career/list a reason u should start a career in digital design. #twitterhomework #mrfoster

I’ve always found it fun how many pathological phenomena are described in terms of food - let’s just say I was inspired today! @KMirza #twitterhomework @loyolapathology

Primary infection of coccidioidomycosis located in the larynx - Spherical cyst with endospore present in the plasma of a multinucleated giant cell #TwitterHomework #Pathelective

Two of the hallmarks of glioblastoma multiforme are microvascular proliferation and necrosis with pseudopalisading tumor cells - the latter of which is seen here #twitterhomework #pathelective @KMirza

Most common genetic mutations in adenocarcinoma of the lung: - KRAS (20-25%) - Poorer prognosis - EGFR (10-15%) - Better prognosis --> respond to treatment with Tyrosine Kinase Inhibitors - ALK (5-7%) - may benefit from treatment with ALK inhibitors #TwitterHomework @kmirza

Pigments are commonly seen and they really stand out. There are 5 types of pigments to look out for 1. Tattoo pigment 2. Hemosiderin 3. Melanin: 4. Lipofuscin: due to "wear and tear" 5. Anthracotic pigment #loyolapathology #twitterhomework @loyolapathology @KMirza

1/3 Salient features of normal parathyroid and common parathyroid tumors. Microscopic images credit: @PathElective lecture by Dr. @nicolecipriani #twitterhomework @KMirza Let's look at the Normal Parathyroid gland first

A new pedagogical paradigm in pathology education #TwitterHomework featuring yours truly with a shout out to @otolaryngolivia! Dedicated to my #PathElective students @loyolapathology @DrFNA @Sara_Jiang @JMGardnerMD @CArnold_GI @PathDocBoston

Amazing to see our #TwitterHomework project led by⭐️resident @HHamnvag and the amazing team of @AustinMcHenry @AadilAhmedMD @aflevent @CArnold_GI published! #TwitterHomework During Pathology Electives: Transforming Pathology Pedagogy | @ArchivesPath

Congenital dyserythropoietic anemia 🔴🔬 Type1- abnormal chromatin structure, chromatin bridges Type 2- binuclearity, multinuclearity Type3- giant multinucleated erythroblasts Variants- 1like, 2like, others #PathTwitter #TwitterHomework

Cytopathology is the study of pathology focusing on disease diagnosis at a cellular level. The first cytopathology test was the Pap test, now routinely used in cervical screening to look for cellular abnormalities. #Cytopathology #Twitterhomework @KMirza

Immunohistochemistry is a technique that allows for visualization of cellular components. In breast cancer, the HER2 stain can be used for diagnosis and treatment planning. #Pathology #BreastCancerAwareness #Twitterhomework @KMirza