#nextgenloading

We have achieved clinical proof of mechanism for AVA6103 (FAP-Exd), our first Next Gen pre|CISION® PDC, in the Phase 1 FOCUS-01 trial. Clean safety profile through 3 dose levels, and clinical PK closely matches preclinical modeling. #NextGenLoading #AVCT

At #ESMO26, we’re presenting the FOCUS-01 trial design and new preclinical data for AVA6103 (FAP-Exd), our first Next Gen pre|CISION® PDC, including activity in Enhertu®-resistant tumor models. #preCISION #NextGenLoading #AVCT

In episode 16 of the R&D Spotlight, the team discusses initial clinical data for AVA6103, pre|CISION® controlled-release exatecan, with two key clinical findings demonstrating proof of mechanism. #NextGenLoading #AVCT

We are delighted to announce our proof of mechanism data with AVA6103. Our #AVCT team is working on making a dent in cancer. The versatility of the preCISION platform now allows us to access previously unaddressable markets. #LetsDoThis #NextGenLoading #HopeWithoutCompromise

Delighted to see #AVCT mentioned in the EndpointsNews round up. AVA6103 data this week were received well. Team are thrilled with the progress. FOCUS-01 Trial continues to escalate. #NextGenLoading #LetsDoThis

Here you will meet a number of folks on our team and understand the motivations behind their amazing work. Pleased to bring you our Wow Moments at #AVCT #NextGenLoading #LetsDoThis

Ask a scientist why they stay in oncology and you will usually hear about a "wow moment". The people behind pre|CISION® share theirs, from the first tumor to plasma data to a new molecule from idea to IND in 12 months. Watch the video here: #AVCT

⚽ De spelers van de 𝐄𝐱𝐜𝐞𝐥𝐬𝐢𝐨𝐫 𝐎𝟐𝟏 zijn vanochtend aan het seizoen begonnen!⁣ Onder leiding van Marinus Barendregt werkten zij hun eerste training af.⁣ ⁣⁣ 👏 𝘎𝘰𝘰𝘥 𝘭𝘶𝘤𝘬 𝘣𝘰𝘺𝘴!⁣⁣ ⁣⁣ 💪⚫️🔴 #samensterk #NextGenLoading

"Education is the most powerful tool you can use to change the world" - Nelson Mandela Some snaps from the next generation of change-makers, problem solvers, go-getters and leaders. #GoRwanda #NextGenLoading

I’ve thought more about the H1 2027 efficacy timing for #AVCT. Avacta never guided to an efficacy readout in 2026. The milestone was always “initial clinical data” in H2 2026, which they’ve now delivered with safety, PK and clinical proof of mechanism. What’s new is that they’ve now clearly signposted “first efficacy data” in H1 2027. That's a big signal to put out early into DL3. But makes sense given what they've told us so far IMO. This is still Phase 1A dose escalation, yet efficacy has now become a specifically defined near term clinical milestone rather than just an exploratory endpoint. The CMO has said they expect to reach DL5/6. That potentially puts a much more mature dataset into early next year.

@tom_the_bomb__ At some point very soon, the wider market will realise that CC, RH and team are executing a very well thought out plan. #LetsDoThis #NextGenLoading #HopeWithoutCompromise #AVCT

Wir starten die nächste Xentral Generation 🚀 Neben dem neuen Produkt gibt es Keynotes von @Westermeyer, @christianreber und spannende Insights von mir. Céline Flores Willers moderiert das ganze Event. Meldet euch an, um dabei zu sein: #nextgenloading

📣ATT: Learners in Kenya Tomorrow, you'll finally get a sneak preview of #AGEC20_KE with registration and Level 0 going live! And so the 24-hour countdown begins... #NextGenLoading #YoungEntrepreneurs

Students from ES Save hard at work in the final weeks of Wavumbuzi... 🔥🚀 #NextGenLoading #AspiringEntrepreneurs

When we talk about popular coaches.. it’s me a by a long shot.. bro the Jr Pios are hilarious.. they lined up waiting to ask the entire Varsity team to sign their gear 🤣😂🤣 #NextGenLoading

💭 "Ik ben blij dat we weer zijn begonnen met trainen. Het is een frisse start in een nieuwe competitie en daarin richten wij ons uiteraard op het hoogste haalbare.” - 𝗘𝘅𝗰𝗲𝗹𝘀𝗶𝗼𝗿 𝗢𝗻𝗱𝗲𝗿 𝟮𝟭 trainer Marinus Barendregt 💪⚫️🔴 #samensterk #NextGenLoading