#sequence

The Homies Put Hands And Feet On Bruh😂 #viral #sequence #explorepage #fight #bar

Ben Johnson is elite at the art of play calling. This is different than standing in front of the chalk board to install. This requires feel for a game. I've never bought the notion that once the game plan has been made, "anybody can call it, most of the work has been done". This is one of the biggest fallacies in football.

@b_peters12 Could argue play sequencing is more important than just being creative on the board. His peers as a player sequencer less than 3 right now

Trick or Treat! Here's Asuna's super duper busty growth drive as a full breast expansion sequence! Did we go too far? do you have any favorite size? She loved them all and so did I! #breastexpansion #sequence #grow

Amatica has closed a multi-million dollar seed round. We're using it to subsidise our test and accelerate building the richest multimodal dataset in chronic neuroimmune disease for AI analysis. What's changing? 🧵

Multi-omics. We're building a multi-omic dataset to integrate multiple data types and power state-of-the-art machine learning research. With consent, every draw banks 5 extra sample types for future multi-omic analysis.

Simpler collection. No processing at the draw: samples ship at room temperature. RNA sequencing runs monthly at our CLIA/CAP accredited lab partner in the US. Results in around two months.

Please and thank you! #Werewolf #Transformation #Sequence #Art 🐺

Not to get political but after watching off. film thru a 2nd time, IMO: -structure adequate -when wrs open sam either didn't find or missed throw -when sam locked in OL wasn't or WRs couldn't get bring in tough catches -run game main issue killing drives -CHI played *very* well

"Sequencing" always looks bad when a run heavy team can't run the ball (personnel driven atm) and can't get explosive (2 high issue that is an OC-transcendent problem) off of hard play action. It starts with OL continuity taking root given all of the changes and injury.

Similar Words. Different Tech. #01 Sequencer vs. Proposer vs. Builder These three terms come up frequently in Ethereum and rollup discussions. They all play a role in transaction processing, but they handle different responsibilities. Here's the difference. 1️⃣ Sequencer - Orders L2 Transactions A sequencer receives transactions, determines their order, and typically produces L2 blocks. Most traditional rollups use a dedicated sequencer, often operated by a single entity. This enables fast confirmations but concentrates transaction-ordering control. 2️⃣ Builder - Constructs L1 Blocks A builder selects, orders, and packages transactions into an Ethereum execution block. Builders optimize block construction to capture transaction fees and MEV (Maximal Extractable Value). Multiple builders can compete to offer the most valuable block to an Ethereum proposer. 3️⃣ Proposer - Proposes L1 Blocks Ethereum selects a validator to propose a block in each 12-second slot. The proposer either builds the block locally or selects one from an external builder, typically through MEV-Boost. It signs and broadcasts the block, while other validators attest through Ethereum's consensus process. How do they work together? Traditional rollup: User → L2 Sequencer → L2 Execution → Batches posted to Ethereum Ethereum L1: Transactions → Builder → Proposer → Consensus 4️⃣ What changes with Puffer UniFi? @puffer_unifi is designed around based sequencing, where canonical L2 transaction ordering is determined through Ethereum L1 rather than an independent L2 sequencer. It introduces two important components: • Gateways: Specialized operators that sequence L2 transactions and provide fast execution preconfirmations. @googlecloud and @gattacahq are registered gateways on @puffer_preconf. • Puffer Preconf: Provides signed execution commitments in milliseconds, backed by staked economic security. In this proposer-delegated based sequencing model, Ethereum proposers delegate sequencing rights to gateways, allowing them to provide fast preconfirmations ahead of L1 block inclusion. Simplified transaction flow: User → Gateway → Preconfirmation + L2 Execution → Ethereum L1 Settlement Puffer UniFi uses gateways and Puffer Preconf to bring fast transaction execution to an Ethereum-aligned rollup architecture.

Anywhere in this letter does it mention Covid?

More than 350 sportspeople - including Olympians Dina Asher-Smith and Tom Daley - have signed a letter to the prime minister calling on him to meet former sprinter Beth Dobbin and commit to increased funding towards ME research.

@fillthewhole The genetics research that's focused on for funding is Sequence ME & Long Covid. The study uses long-read whole-genome sequencing to analyze the genetic codes of 9,000 people with ME/CFS and 9,000 people with Long Covid.

Man ✌🏾💀

@GrubAtGenos This is more about play sequencing than anything

EEZ went live with their docs and three demos. Extending the L1 is a recurring theme across the demos: - Tapping liquidity from the L1 for a CoW order - Using L1 as root of trust for a Safe owner change - Authorising an L1 transfer from a rollup Increasing L1 utility deepens its function as a centre of gravity for the Ethereum economy. Kudos to the team!

The devs did something. Many things, as it turns out. Not one, but THREE firsts for synchronous composability between a rollup and Ethereum mainnet. @tw_tter and @eduadiez will demo them live on Lotus Stage 1 at Devcon, 13:00 IST. We even had the devs make their own launch video. Cast, in order of appearance: @SCBuergel , @antonimarber, @chetnamiittal, @debjitbw, @JesusLigero3, @jbaylina , @turingtestrun, @eduadiez, @filoozom, @epochzer0, @tw_tter , and @0xKenk . One @ethereum . Details of the news and the demos in thread. 🧵

@5dayoldburrito @barnabemonnot No bridges, no chain hopping. it's not so much about the efficiency gains from this, than the UX for the user.

@materkel @barnabemonnot I love the idea since it’s bringing us closer to the intended idea of Ethereum. But I’m trying to wrap my head around it if this actually solves a problem that Ethereum needs Rollups like Base and RH will not use the EEZ since they have to forfeit their sequencing fees.

'Ancient DNA revealed a lost human population that appears to have gone extinct 45,000 years ago—and it changes everything we thought we knew' [again!]

@ChrisStringer65 I'm sceptical, bc prehistoric DNA is extremely fragmented & most parts are added by computers with some kind of "best guessing". Ordinary people only receive these spectacular articles, but never the scientific discussions or disprovals following such "break through's".

@Wieser_J_ @ChrisStringer65 That’s not correct. Published paleogenomes are reconstructed using sophisticated methods for extracting ancient DNA coupled with ever-improving sequencing technologies. The underlying DNA sequence data are generally robust and reproducible. The computational genomics analyses….

As someone @plasmidsaurus who regularly deals with vendors or CROs/CMOs that require a several step, multiday, 5+ emails, process to place one order or even get a quote, I can see why we weird people out when most of our sequencing service is one extra click more than amazon

[#WJSN] #우주소녀 SPECIAL SINGLE ALBUM #Sequence 🫧 #CONCEPT_PHOTO Take 1 Ver. 2022.07.05 #COMING_SOON 🫧💙 #Last_Sequence #라스트_시퀀스 #WJSN_Sequence #우주소녀_Sequence #우주소녀_시퀀스 #COMEBACK #우주소녀_컴백

Similar Words. Different Tech. #03 Traditional Sequenced Rollups vs. Based Rollups Most Ethereum rollups rely on Ethereum for settlement, but they don't necessarily rely on Ethereum for transaction ordering. So who actually decides which transactions go first? 1️⃣ Traditional Sequenced Rollups Most rollups operate their own sequencer, often controlled by a single organization. The sequencer receives transactions, determines their order, and produces L2 blocks. This enables fast confirmations, but transaction ordering is controlled by infrastructure separate from Ethereum's validators. 2️⃣ Based Rollups Based rollups take a different approach. Instead of relying on an independent L2 sequencer for canonical ordering, they derive it from Ethereum L1. This aligns sequencing with Ethereum's proposer and builder infrastructure. But there's an important distinction: Based sequencing doesn't automatically mean fast confirmations or synchronous composability. These require additional mechanisms. 3️⃣ How @puffer_unifi Approaches This Puffer UniFi is designed to combine Ethereum-aligned sequencing with fast execution and cross-layer composability. Its stack brings together: • Based sequencing: Ethereum L1-derived canonical ordering, with proposer delegation on the roadmap. • @puffer_preconf: Gateway-based execution commitments that provide early transaction assurance before L1 settlement. • Signal Service: Designed to enable same-slot L1→L2 communication. • Multi-TEE proving: Supports rapid verification of L2 execution for cross-layer operations. Together, these components aim to make applications more responsive while enabling tighter interaction with Ethereum L1 liquidity and smart contracts. The takeaway: Traditional vs. based sequencing is about who controls transaction ordering. Fast confirmations and synchronous composability are separate engineering challenges. Puffer UniFi is designed to address all three.

𝗚𝗲𝗻𝗼𝗺𝗲𝘀 𝗮𝗿𝗲 𝘀𝗼𝘂𝗿𝗰𝗲 𝗰𝗼𝗱𝗲. 𝗜𝘁'𝘀 𝘁𝗶𝗺𝗲 𝘄𝗲 𝗺𝗮𝗻𝗮𝗴𝗲𝗱 𝘁𝗵𝗲𝗺 𝗹𝗶𝗸𝗲 𝗶𝘁. (The git moment for genomics) This month The Bioinformatics Company unveils 𝗚𝗟𝟭-𝘀𝗲𝗾 — and the preprint behind it. One protocol that treats DNA, RNA and protein sequences the way git treats code: content-addressed, versioned, diffable, auditable. Two layers. The separation is the point. 𝗟𝗮𝘆𝗲𝗿 𝟭 — 𝗣𝘂𝗯𝗹𝗶𝗰 𝗿𝗲𝗳𝗲𝗿𝗲𝗻𝗰𝗲, 𝗼𝗻 𝗰𝗵𝗮𝗶𝗻 The 𝗰𝗼𝗺𝗽𝗹𝗲𝘁𝗲 𝗵𝘂𝗺𝗮𝗻 𝗿𝗲𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗴𝗲𝗻𝗼𝗺𝗲 (𝗚𝗥𝗖𝗵𝟯𝟴) — every base, in full, in chain state on GenesisL1. Not a hash. Not a pointer. The sequence itself, in GL1-seq's native ~2-bit encoding, 4× denser than FASTA. One canonical sequence, verifiable by anyone: the main branch the world commits against. Every other genome is a diff. A full human genome as a diff is 𝟭𝟬–𝟮𝟬 𝗠𝗕 — and thousands of genomes on chain become routine. At launch: the 𝗰𝗼𝗺𝗽𝗹𝗲𝘁𝗲 𝗵𝘂𝗺𝗮𝗻 𝗿𝗲𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗴𝗲𝗻𝗼𝗺𝗲 (𝗚𝗥𝗖𝗵𝟯𝟴) + 𝟭𝟮 𝗽𝗶𝗹𝗼𝘁 𝗴𝗲𝗻𝗼𝗺𝗲𝘀. Next: 𝟭,𝟬𝟬𝟬+ public genomes, then Swiss-Prot, RefSeq, UniRef50, IMGT/HLA and antibody repertoires. Not theory. GenesisL1 already holds 𝟭𝗠+ PDB and AlphaFold structures in chain state (MolNFT). Sequences are next. 𝗟𝗮𝘆𝗲𝗿 𝟮 — 𝗣𝗿𝗶𝘃𝗮𝘁𝗲 𝗱𝗮𝘁𝗮, 𝗶𝗻 𝗮 𝗰𝗼𝗺𝗽𝗹𝗶𝗮𝗻𝘁 𝗲𝗻𝘃𝗶𝗿𝗼𝗻𝗺𝗲𝗻𝘁 Patient and participant genomes 𝗻𝗲𝘃𝗲𝗿 𝘁𝗼𝘂𝗰𝗵 𝘁𝗵𝗲 𝗰𝗵𝗮𝗶𝗻. They remain in the institution's private, compliant environment — under its own governance, access controls and jurisdiction. The chain records only cryptographic commitments — a fingerprint, never the sequence. Provenance and change history, verifiable by anyone, with zero data leaving the institution. 𝗪𝗵𝗮𝘁 𝗶𝘁 𝗱𝗲𝗹𝗶𝘃𝗲𝗿𝘀 🔹 𝗟𝗼𝘀𝘀𝗹𝗲𝘀𝘀 𝗯𝘆 𝗰𝗼𝗻𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝗼𝗻 — bit-exact reconstruction from reference + commits. 100% fidelity. 🔹 >𝟰× 𝗳𝗮𝘀𝘁𝗲𝗿, >𝟰× 𝗰𝗵𝗲𝗮𝗽𝗲𝗿 — touch the delta, never the full sequence. 🔹 𝗣𝗿𝗼𝘃𝗲𝗻𝗮𝗻𝗰𝗲 𝗮𝗻𝗱 𝗮𝘂𝗱𝗶𝘁 𝗯𝘂𝗶𝗹𝘁 𝗶𝗻 — who, what, derived from what. Reproducibility becomes a property of the data. 🔹 𝗗𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗶𝘀𝘁𝗶𝗰 𝗲𝘃𝗲𝗿𝘆𝘄𝗵𝗲𝗿𝗲 — identical results on-chain (EVM) and off-chain, in Python, JavaScript, Go, Rust and C++. No protocol upgrade required. 🔹 𝗡𝗮𝘁𝗶𝘃𝗲 𝘁𝗼 𝗵𝘂𝗺𝗮𝗻𝘀 𝗮𝗻𝗱 𝗔𝗜 𝗮𝗴𝗲𝗻𝘁𝘀 — one format, one interface. Agents branch, analyze and commit with full attribution; humans audit every step. For biobanks, sequencing cores, national genome projects, pharma and regulators: one canonical reference everyone shares, plus a tamper-evident audit trail for private data — 𝘄𝗶𝘁𝗵𝗼𝘂𝘁 𝗺𝗼𝘃𝗶𝗻𝗴 𝗮 𝘀𝗶𝗻𝗴𝗹𝗲 𝗽𝗮𝘁𝗶𝗲𝗻𝘁 𝗴𝗲𝗻𝗼𝗺𝗲. Preprint, benchmarks and code this month — follow for the release. #Genomics #Bioinformatics #DeSci #DataProvenance #AIAgents #GenesisL1

.@Intuit expands industry roster for Intuit Enterprise Suite, steps up midmarket game Intuit launched industry focused versions of its Intuit Enterprise Suite, automated revenue management via its Sequence acquisition, a context layer powered by Intuit…

How to request access to our free, self-paced phage #Bioinformatics training. Got #phage sequencing data but no idea where to start? Our free, self-paced #courses take you from your very first terminal command to comparing phage #genomes, etc. Join Us...

CeGaT (@CeGaT_GmbH) will be joining us on the FOG London exhibition floor this January! Meet the team, explore their sequencing and genomic analysis services, and connect with the genomics community. Register here:  #FOG2027 #Genomics #NGS

🐨 #Sequence #boardgame became my favourite #game since yesterday lol #sydney Friday at friends to celebrate his new software engineering job and moving to Brisbane

Ten thousand followers in ninety days is not a content problem. It's a distribution problem wearing a content costume. The founders who actually get there start with one market problem that can produce a post every single day. Month one, I would not mention the product once. Nobody cares yet. I'd publish around the pain it solves, broken workflows, expensive manual work, revenue quietly leaking out the side door. Skip this part and the launch happens to a room that was never warmed up. The product looks average because nobody understood the problem it was solving. The content itself wouldn't come from a whiteboard. It would come from sales calls, demo drop offs, support tickets, and the comment section. If the same objection shows up three times in a week, that's not feedback. That's tomorrow's post. I wouldn't chase reach on every post. A post built for shares looks different from one built for demo requests, and stacking every goal into one caption is how you end up with a post that gets seen and forgotten in the same scroll. Pick the one job before you write the caption, not after. Publishing isn't the finish line, it's the starting gun. Real replies. Founder to founder conversations. Podcast clips. Newsletter repurposing. Employees reposting with their own take. One good post, worked properly, becomes ten distribution assets. I'd track this before I ever tracked followers: Are founders quoting the content on sales calls? Are investors engaging more than once? Are prospects showing up to the demo already convinced? The day those three signals show up in the same week, the follower count stops being the target and starts being math you don't need to check anymore. #StartupMarketing #AIStartups #GrowthMarketing #FounderBranding #ContentStrategy #B2BMarketing #SaaSMarketing

@usama_shaX Building around pain before mentioning product is smart sequencing