Mancias Lab

@ManciasLab

#PancreaticCancer Research Lab interested in selective #autophagy, iron, therapeutic resistance, and #proteomics. @DanaFarber, @BrighamWomens, @harvardmed

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  1. Mancias Lab@ManciasLab
    Mancias Lab
    RT @SantanaCodina: Excited to share our latest story @NatureComms. Here, we used quantitative proteomics, metabolomics and in vitro/in vivo CRISPR screens to define mechanisms of resistance to DHODHi in PDAC and propose combinatorial approaches with BCL-XL inhibitors:
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  2. Mancias Lab@ManciasLab
    Mancias Lab
    RT @iDikic2: How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer? A new role for an autophagy receptor IRGQ in this process with a clinical relevance for the development of liver carcinoma in humans and mice 😊😀
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  3. Mancias Lab@ManciasLab
    Mancias Lab
    RT @AACR: During the keynote addresses at #AACRpan24, Eileen M. O’Reilly and Joseph D. Mancias discussed how understanding pancreatic cancer’s strengths can help researchers uncover its weaknesses. Learn more on the #AACRBlog: @EileenMOReilly @ManciasLab
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  4. Mancias Lab@ManciasLab
    Mancias Lab
    RT @AACR: Joseph D. Mancias discussed "Targeting Autophagy in Pancreatic Cancer" in a Rising Star Keynote Lecture during the AACR Special Conference on Advances in Pancreatic Cancer Research. #AACRpan24 @ManciasLab
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  5. Mancias Lab@ManciasLab
    Mancias Lab
    RT @Aiims1742: The (almost) full program is now online with an amazing lineup of speakers! #AACRPan24 @EileenMOReilly @ManciasLab @DrJashDatta @TeresaZimmers @DrHendifar @JanowitzTobias @wantong_yao @MaraShermanLab @KenOliveLab @andrewaguirremd @cjder23 @bryant_kl @pratt_ed @mggoggins @ChristieTowers @Cosimo_Commisso @Chiolaboratory @nada_kalaany and those not on Twitter. See you all in Boston! @AACR #PancreaticCancer
    Anirban Maitra @Aiims1742
    Abstract submissions are now open for the @AACR special conference on #PancreaticCancer #AACRPan24 Outline of proposed program below:
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  6. Mancias Lab@ManciasLab
    Mancias Lab
    RT @SantanaCodina: WE ARE HIRING! We are looking for a motivated postdoc to work on a fully-funded project studying the role of iron metabolism in drug resistance in pancreatic cancer. 3 weeks left to apply. Please spread the word.
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  7. Mancias Lab@ManciasLab
    Mancias Lab
    RT @LGlimcherMD: We are so inspired by patients like Candace and her experience. With a loving and supportive family and the latest treatments at @DanaFarber, Candace is a source of hope for more patients with pancreatic cancer.
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  8. Mancias Lab@ManciasLab
    Mancias Lab
    RT @LGlimcherMD: Researchers at @DanaFarber and other institutions recently made important discoveries into the recycling system of pancreatic cancer cells, a promising step toward targeted therapies for one of the most challenging cancers.
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  9. Mancias Lab@ManciasLab
    Mancias Lab
    RT @DanaFarber: Pancreatic cancer cells operate a recycling program that would be the envy of any municipality — but the only beneficiaries are the cells themselves.
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  10. Mancias Lab@ManciasLab
    Mancias Lab
    RT @jonathan_nowak: Latest Wolpin-Nowak lab paper on single cell, in situ protein-based characterization of transcriptional subtypes in pancreatic cancer now out in @CR_AACR
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  11. Mancias Lab@ManciasLab
    Mancias Lab
    RT @LyssiotisLab: 🚨Job Posting: The @YatrikShahLab & @LyssiotisLab are looking for a postdoc to study the role of iron, O2, & metabolism in erythropoiesis. Opportunities to learn and employ multiple cutting-edge technologies in 2 ~pretty cool labs 😁 DM with interest.
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