Payne Research Group

Excited to share our work on mirror-image reprogrammed mRNA display, out now in @J_A_C_S! We discovered a cyclic D-peptide ligand of CCL22 with nanomolar inhibition - by going through the looking glass, we ended up in D-wonderland 🪞✨ @ARC_CIPPS

RT @nchembio: Monoclonal antibodies against pseudaminic acid (Pse) – present in bacterial LPS, capsular polysaccharides, and glycoproteins – have been developed that enable Pse glycoproteome profiling and show therapeutic potential #glycotime

RT @Sydney_Science: Congratulations to Associate Professor @YuHengLau, Professor Richard Payne and Professor Tony Weiss who have received @nhmrc Investigator Grants! Find out more about their projects: #LeadershipForGood

RT @WinssingerLab: Our work on reversible anticoagulant was featured on the cover of Nature Biotechnology.  If you are curious about the technology here is an accessible podcast from the W-lab science talk - Anticoagulants that can be reversed, if need be:

RT @YuHengLau: Big crowd to see Prof Sir Shankar Balasubramanian @ChemCambridge give the 2025 Cornforth Lecture @Sydney_Science @SydneyChemistry Very happy for all the students who have seen his science in my undergraduate lectures... They finally get to see him now in action for real! 🧬

Delighted to have our mirror image cyclic sulfopeptide display work highlighted on the @ampepsoc website!

Congratulations @mark_larance and team for this beautiful work just published in @nchembio #glycotime

Our collaborative paper showing that FUT10 and FUT11 are protein O-fucosyltransferases (POFUTs) modifying proteins with EMI domains is out in @nchembio. Great collaboration with Prof. Robert Haltiwanger’s lab @UGAResearch, @CPC_usyd, @syd_health, @ozglyco.

Happy holidays to all our friends and collaborators around the world! 🎉🎄🎁

Very excited to have our work published in @JOC_OL!! We used a divergent strategy for the total synthesis of a family NRP natural products, the rufomycins. Huge congrats to @BeddingMax, @BrytonForster, and everyone else involved. @ARC_CIPPS

RT @PetersenChemLab: Next up: Jonathan’s work on the photocatalytic synthesis of indolyl-isoxazolines just accepted in @EurJOC ( 🎉Congrats to him and the team!🎉 @farhiii @UnsworthChem @PayneResearch Stay tuned for more from Jono by checking out the @JamesLabChem !

RT @J_A_C_S: Discovery of Selective Cyclic d-Sulfopeptide Ligands of the Chemokine CCL22 via Mirror-Image mRNA Display with Genetic Reprogramming | JACS @Sydney_Uni #CyclicSulfoPeptide #Chemokine #Ligand #MirrorImage #mRNA #Display #GeneticReprogramming

RT @Z_belinda: Proud to announce that my first firsty has now been published in @J_A_C_S! We used mirror-image reprogrammed mRNA display to discover a nanomolar cyclic D-sulfopeptide inhibitor of CCL22! @ARC_CIPPS @SydneyChemistry

RT @LechtenbergLab: Thanks to first author @xiangyi_susie, all members of my lab as well as collaborators and co-authors in the @komander_lab (@WEHI_research), @ethangbaus (WEHI) and @PayneResearch (@Sydney_Uni) labs.

Thank you @CBBaileyLab for an amazing talk today at #CIPPS2024 - who knew bacteria were such great organic chemists?! @ARC_CIPPS

Excited to hear more about dehydroalanine from group alumnus Andrew Giltrap of the Davis lab at @RosFrankInst! #CIPPS2024 @ARC_CIPPS

Great work by associate investigator Mark Larance - discovering a new PTM is not easy! Looking forward to seeing the story come out in @nchembio soon. #CIPPS2024 @ARC_CIPPS

Great job Liam and @AnthonyAyoub00 on their flash and full talks today! For more, find Liam at poster 20 tonight at #CIPPS2024 @ARC_CIPPS

Thank you to Dr Jess Smith from Brandon Capital for inspiring us to develop a path to commercialize our research, and hence have further impact with our science! #CIPPS2024

Bryton and Pat from the group gave fantastic flashtalks about their projects targeting infectious diseases at #CIPPS2024! Check out their posters no. 1 and 11 tomorrow @ARC_CIPPS

Kicking off the @ARC_CIPPS conference associate investigator talks with an amazing presentation from Wai-Hong Tham of ANU and @WEHI_research. Nanobodies are on the rise! #CIPPS2024