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Dikic lab

@DikicLab

Research group of @iDikic2 at @IBC2_GU. ubiquitination, autophagy, host-pathogen interactions

79 Following1.2K Followers141 Posts
  1. Dikic lab@DikicLab
    Dikic lab
    RT @proxidrugs: 🎙️Honored to enjoy insightful presentations on “RNA-based therapeutics” & “New targets & therapeutic approaches” on day 2 of the 1st Symposium on Advances in Therapeutic Approaches.🙏Thanks to all speakers & participants for their valuable contributions. @BMBF_Bund @HMWK_Hessen
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  2. Dikic lab@DikicLab
    We are making a move ➡️🦋 Follow us there:
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  3. Dikic lab@DikicLab
    🤩It's out! Check out our latest paper describing an optimised #CRBN that we used for high-throughput drug screening and developing new chemo-proteomic assays. #HTS #TPD @proxidrugs @IBC2_GU @goetheuni
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    Cell Chemical Biology @CellChemBiol
    Online! An engineered cereblon optimized for high throughput screening and molecular glue discovery by Henry Bailey, Jonathan Eisert, Fiona Sorrell @Fi_in_Frankfurt, Ivan Dikic @iDikic2 @DikicLab et al at @goetheuni @IBC2_GU @MPIBP @merckgroup
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  5. Dikic lab@DikicLab
    *See, share, register* for the Frankfurt Conference on Quality Control in Life Processes, 24-27th of March. The speaker's lineup looks amazing already!! 🤩 👉Registration before 1st of December: #FCQC2025 #autophagy #proteostasis #ubiquitin
    SFB 1177 @sfb1177
    Excited to announce the keynote speakers at #FCQC2025! Aaron Ciechanover from @TechnionLive and @dixitvishva from @genentech Stay tuned for more updates and don't forget to register! #autophagy #ubiquitin #TPD #UPS #signaling
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  7. Dikic lab@DikicLab
    Dikic lab
    RT @sfb1177: 🔔 Registration deadline approaching! Don't miss out and secure your spot now! 🔗 #FCQC2025
    SFB 1177 @sfb1177
    #FCQC2025: Registration open Join us for a high-caliber line-up of talks on quality control mechanisms & networks, the interplay of autophagy & ubiquitin in health & disease, novel therapeutics using the ubiquitin system. #proteostasis #autophagy
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  8. SFB 1177@sfb1177
    #FCQC2025: Registration open Join us for a high-caliber line-up of talks on quality control mechanisms & networks, the interplay of autophagy & ubiquitin in health & disease, novel therapeutics using the ubiquitin system. #proteostasis #autophagy
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  10. Dikic lab@DikicLab
    7th year in a row that Ivan is on the @Clarivate Highly Cited Researchers list. Congratulations @iDikic2 , and a big thank you to all the team members, past & current collaborators and colleagues. #HighlyCited2024 @ClarivateAG @goetheuni @IBC2_GU
    IBC2 @IBC2_GU
    🥳 Proud to see IBC2 Director @iDikic2 on the #HighlyCited2024 list for the 7th year in a row! Congratulations to all @goetheuni colleagues on the list - @StefanieDimmel1, @HummerLab, Florian Greten, Sibylle Loibl & Stefan Offermanns
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  12. Dikic lab@DikicLab
    Dikic lab
    RT @iDikic2: How changes in kinetics of #splicing can lead to proteotoxic cell death & what is the role of #ubiquitination and ER-phagy in this process? Congrats to Cristian & all collaborators for this fascinating discovery 👏 More info:
    Cristian Prieto-Garcia @CristianPG_mlg
    It is finally out! My first @ScienceMagazine paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor @iDikic2 for all the support and trust ! 🫶. Science
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  13. Cristian Prieto-Garcia@CristianPG_mlg
    It is finally out! My first @ScienceMagazine paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor @iDikic2 for all the support and trust ! 🫶. Science
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  14. Dikic lab@DikicLab
    Excited to share our latest research published in @ScienceMagazine! Cryptic splicing can lead to proteotoxic stress, but how do cells cope? Our study uncovers the role of ubiquitination and ER-phagy in mitigating the effects of misfolded proteins.
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  17. Dikic lab@DikicLab
    Dikic lab
    RT @JT_MVieira: I am very happy to have had the opportunity to present our latest results on targeting #legionella with #protacs. Especially in a session with such renowned scientists. Thanks to Antje Flieger and her team at @rki_de for organising this meeting.
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  18. Dikic lab@DikicLab
    We can’t wait for this conference!😍4 days to talk about quality control mechanisms, the interplay between #autophagy and #ubiquitin and emerging therapeutics utilising the ub system. Registration Deadline: 1st Dec #FCQC2025 @goetheuni
    Women in Autophagy @WAutophagy
    SAVE DATE: March 24-27, 2025, in Frankfurt. "4th Frankfurt Conference on Quality Control in Life Processes".
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  19. Dikic lab@DikicLab
    Dikic lab
    RT @CristianPG_mlg: Really happy to take part of this amazing manuscript from @crypt_tales and @DiefenbacherL published in @oncogenejournal . USP10 promotes colorectal cancer and stemness. #ubiquitin #cancerResearch 🫶👏🏻
    Michaela Reissland @crypt_tales
    🥳I am beyond to finally share the story of my PhD out now: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer Lets have a little look what we found: 🧵1/11
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  20. Michaela Reissland@crypt_tales
    🥳I am beyond to finally share the story of my PhD out now: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer Lets have a little look what we found: 🧵1/11
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  22. Dikic lab@DikicLab
    Dikic lab
    RT @CristianPG_mlg: Really happy to contribute with mouse liver cancer models and human cancer data analyses to this amazing Cell paper from @iDikic2 and Herhaus lab. Huge congrats to Lina, Uxia, Ivan and other authors from @jwadeharperlab , @ManciasLab, @DikicLab, etc.👏🏻
    Cell @CellCellPress
    Now online! IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion
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  23. Dikic lab@DikicLab
    Dikic lab
    RT @CellCellPress: Now online! IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion
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  25. Dikic lab@DikicLab
    Posts @DikicLab
    We identified IRGQ as a key regulator of MHC-I quality control. Its absence enhances CD8+ T cell responses. Reduced IRGQ levels in hepatocellular carcinoma patients and mouse models lead to improved survival by promoting anti-tumour immunity. #CancerResearch #Immunotherapy
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  27. Women in Autophagy@WAutophagy
    SAVE DATE: March 24-27, 2025, in Frankfurt. "4th Frankfurt Conference on Quality Control in Life Processes".
    Download
    03128.3K
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