#Transcriptome

🌟 Read the exciting stories highlighting new methods and resources for #genomics and new mechanisms in host-pathogen interactions: Now published in the October issue of #G3journal 🧵

@MLstiburek ☕️ The fungal pathogen Hemileia vastatrix causes Coffee leaf rust that has affected Arabica coffee production for centuries. A new genome of H. vastatrix identifies a haploid trisomy that may be responsible for the pathogen's changed virulence profile. 🔗

@MLstiburek 🪱 Identifying connections between genetic and phenotypic variation is important to studying host-parasite interactions. A #transcriptome analysis shows how host plant genes respond differently based on the genetic background of an infecting #nematode. 🔗

#Transcriptome-wide profiling of #piRNA targeting rules provides new insights into the interplay between #Argonaute pathways and their physiological roles in #Celegans. -->

How do the #genome, #epigenome and #transcriptome co-evolve in colorectal #cancer? In the second of two papers in @nature, we find gene expr is not strongly heritable & evaluate "driverness" of muts directly in patient tumours @AndreaSottoriva #EPICC2 1/7

The Human #Transcriptome Cell Atlas provides a one-stop interactive query to #gene signatures, transcription factor (TF) activities, TF motifs, receptor–ligand interactions, enriched #geneontology (GO) terms, etc. across cell types... @karolinskainst

🌱 🪱 In #G3journal, a #transcriptome analysis identifies that host plant genes respond differently based on the genetic background of an infecting endoparasitic #nematode. 🔗

Unlocking the pathophysiological landscape of failing hearts: the importance of cell-enriched and histology-specific transcriptome mapping #heart #failure #transcriptome #EHJ #Cardiotwitter @ESC_journals @escardio

Measuring natural selection on the #transcriptome 📖 Viewpoint article by Stinchcombe and Kelly @JohnStinchcombe @WileyPlantScience #PlantScience

Evolutionary divergence in embryo and seed coat development of U’s Triangle #Brassica species illustrated by a spatiotemporal #transcriptome atlas The next in our Community resources series 👇

#SpatialOmics Spatial-DMT Co-profiling spatial #DNAMethylome #Transcriptome🤠 Enzymatic Methyl-seq (pooling 5mC 5hmC) >100k CpG, >1k gene per 10-μm pixel Mapping mCG & mCH & transcription factors @ChinNLee2021 @zhouwanding @DengYanxiang bioRxiv 2025

Excited to share a 🆕 #OpenAccess article "#Tropine alkaloid-driven panomic🧬 (#transcriptome–#metabolome) reprogramming delivers insights into #cold❄️ tolerance in #rapeseed 🪴" from my PhD-lab is out in PPB 🥳🎊 🖇️ @sci_plant @plantsciences @StressPlant

Single-cell sequencing of the small-RNA #transcriptome @karolinskainst #stemcells

Simultaneous single-cell protein and #transcriptome analysis identifies a baseline immune circuit associated with antibody responses to #vaccination in healthy individuals and the severity of disease flares in patients with a subtype of #lupus @NIH .

#Transcriptome-scale RNase-footprinting of RNA-protein complexes

Transcriptome-Wide, Unbiased Profiling of Ribonuclease Targeting Chimeras | Journal of the American Chemical Society @disney_lab @UFScripps @scrippsresearch #Transcriptome #Profiling #Ribonuclease #Chimeras

Salmon - a tool for fast transcriptome-wide abundance assessment. ($) #transcriptome

Out now! Whole-exome and #transcriptome meta-analysis of patients treated with #immune checkpoint blockade reveals #cell-intrinsic mechanisms of sensitization to checkpoint inhibition. @SwantonLab @CR_UK

scRNAseqで定義された皮質興奮性neuron型は局所形態/電気生理だけでなく長距離軸索投射(projectome) まで予測し得る mouse視覚皮質でPatch-seqと全脳軸索形態を統合し17興奮性細胞型の遺伝子/形態/発火/投射対応を解明 OA #network #transcriptome #papers

Single-cell #RNAseq #scRNAseq reveals the #transcriptome of the #aging #Drosophila #brain in unprecedented resolution. Read it now in Cell from Stein Aerts & co at @KU_Leuven

"Imbalance of regulatory and cytotoxic SARS-CoV-2-reactive CD4+ T cells in COVID-19" - See more from this article in @CellCellPress #immunity #tcells #transcriptome

New resource out now! During #development the #transcriptome and the #3D #genome are extensively transformed in the first post-natal month, independent of sensory experience @Harvard